2. Natural Products
  3. Marine natural products
  4. Marine microorganism

Marine microorganism

Marine microorganism (57):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15141
    Staurosporine 62996-74-1 99.77%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer.
    Staurosporine
  • HY-10985
    Marizomib 437742-34-2 99.13%
    Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1) and trypsin-like (T-L, β2) activities of the 20S proteasome (IC50=3.5, 28, and 430 nM, respectively).
    Marizomib
  • HY-N0108
    Physcion 521-61-9 99.40%
    Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells.
    Physcion
  • HY-N6769
    Radicicol 12772-57-5 99.96%
    Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation. Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM.
    Radicicol
  • HY-W001963
    Pyrrole-2-carboxylic acid 634-97-9 99.96%
    Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov. Pyrrole-2-carboxylic acid is a biological form of pyrrole that is often encountered in natural compounds. Pyrrole-2-carboxylic acid serves as a precursor for various pyrrole derivatives like clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin in biosynthetic processes.
    Pyrrole-2-carboxylic acid
  • HY-N17166
    Cristatumin E 1459722-08-7
    Cristatumin E (Eurocristatine) is a natural alkaloid.
    Cristatumin E
  • HY-113507
    PC(O-16:0/18:2(9Z,12Z)) 88542-95-4
    PC(O-16:0/18:2(9Z,12Z)) is a phospholipid. PC(O-16:0/18:2(9Z,12Z)) serves as a substrate for Phospholipase A2.
    PC(O-16:0/18:2(9Z,12Z))
  • HY-N8310
    Tunicamycin A1 66081-37-6
    Tunicamycin A1 (Tunicamycin 14:1; Tunicamycin II; Tunicamycin C) is an antibiotic. Tunicamycin A1 exhibits antibacterial activity against a variety of bacterial. Tunicamycin A1 can be used in studies related to bacterial infections.
    Tunicamycin A1
  • HY-113604
    Pentabromopseudilin 10245-81-5 99.63%
    Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer.
    Pentabromopseudilin
  • HY-N6744
    Chaetoglobosin A 50335-03-0 99.07%
    Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia.
    Chaetoglobosin A
  • HY-N7078
    Spiculisporic acid 469-77-2 99.88%
    Spiculisporic acid is a γ-butenolide isolated from the cultue of Aspergillus sp. Spiculisporic acid is a microbial biosurfactant and has anti-oxidative stress actions.
    Spiculisporic acid
  • HY-N12614
    Diorcinol 20282-75-1 99.30%
    Diorcinol is a potent SHP1 inhibitor with an IC50 value of 0.96 μM. Diorcinol can be isolated from Aspergillus sydowii. Diorcinol has good blood-brain barrier penetration and can be used for diabetes research.
    Diorcinol
  • HY-113972
    Methyl mycophenolate 31858-66-9 99.0%
    Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae.
    Methyl mycophenolate
  • HY-N9251
    Cyclo(Ile-Ala) 90821-99-1 98.47%
    Cyclo(Ile-Ala) is found in marine actinomycete 11014 I..
    Cyclo(Ile-Ala)
  • HY-15141R
    Staurosporine (Standard) 62996-74-1
    Staurosporine (Standard) is the analytical standard of Staurosporine. This product is intended for research and analytical applications. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer[1][2][3][4][5].
    Staurosporine (Standard)
  • HY-N8275
    (R)-(+)-Citronellic acid 18951-85-4 99.45%
    (R)-(+)-Citronellic acid is a chiral carboxylic acid and can be used as a drug intermediate.
    (R)-(+)-Citronellic acid
  • HY-N12613
    Sydowimide A
    Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC50 values of 1.5, 2.4 and 18.83 μM, respectively.
    Sydowimide A
  • HY-121133
    (-)-Cyclopenol 20007-85-6 99.42%
    (-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .
    (-)-Cyclopenol
  • HY-126708
    Luisol A 225110-59-8 99.91%
    Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog.
    Luisol A
  • HY-N18050
    Petrobactin 545434-89-7
    Petrobactin is a photoreactive siderophore. Petrobactin can be produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. Petrobactin can be synthesized by Bacillus anthracis str. Sterne under conditions of iron starvation. Petrobactin readily undergoes a light-mediated decarboxylation reaction when bound to Fe(III).
    Petrobactin